Publications

Selected Works

The homepage keeps the two current works in focus. This page keeps the wider project and publication record together for later expansion.

01Preview for Aggregating Epigenetic Methylation Signals for Improved Long-Read Genetic Variant Calling
2025 GIW ISCB-Asia 2025

Aggregating Epigenetic Methylation Signals for Improved Long-Read Genetic Variant Calling

First-author poster on methylation-assisted long-read variant calling.

Junzhe Li, Zhenxian Zheng, Ruibang Luo

GenomicsVariant CallingMethylationLong-Read Sequencing
02Preview for DuetRNA: Base-and-Sugar Dual-Frame Flow Matching for RNA Co-Design
2025 Research project

DuetRNA: Base-and-Sugar Dual-Frame Flow Matching for RNA Co-Design

Generative modeling for RNA backbone structures with inertial frames and flow matching on rigid-body manifolds.

Junzhe Li, Lijian Peng, Yuhao Li, Yize Zhou, Hanqun Cao, Cheng Tan, Shengchao Liu

RNA DesignFlow MatchingSE(3) InvarianceRigid Body Dynamics
03Coming soon
2025 Research project

Methylation-Augmented Variant Calling with Clair3

Improving long-read variant calling by incorporating methylation signals for better read phasing.

GenomicsVariant CallingMethylationLong-Read Sequencing
04Coming soon
2025 Research project

4D Human-Object Interaction Dataset Construction

Dataset construction and scene reconstruction for indoor human-object interaction.

4D ReconstructionDiffusion ModelsHuman-Object Interaction
05
2025 Publication

Clair-Mosaic: A deep-learning method for long-read mosaic small variant calling

Preprint on deep-learning long-read mosaic small variant calling.

Lei Chen, Zhenxian Zheng, Minggao He, Angel On Ki Wong, Xian Yu, Junzhe Li, Jingcheng Zhang, Yekai Zhou, Ruibang Luo

BioinformaticsDeep LearningVariant Calling
06
2025 Publication

Accelerated long-read variant calling with Clair3 for whole-genome sequencing

Submitted work on accelerated long-read variant calling with Clair3.

Zhenxian Zheng, Minggao He, Xian Yu, Junzhe Li, Lei Chen, Angel On Ki Wong, Jingcheng Zhang, Yekai Zhou, Ruibang Luo

BioinformaticsVariant CallingLong-Read Sequencing